Home / Non‐Biological Complex Drugs / Research / Biosimilars and follow-on NBCDs for MS in Europe, the US and Canada
Biosimilars and follow-on NBCDs for MS in Europe, the US and Canada Posted 19/01/2018

The advent of biological medicines has significantly transformed the landscapes of many disease spaces and improved the lives of millions around the world. However, the structural complexity and sensitivity of such products result in a high price tag, adding to already financially strained healthcare systems. As these and other expensive complex drugs lose market exclusivity, stakeholders eagerly await the arrival of lower cost alternatives, such as biosimilars and follow-on non-biological complex drugs (NBCDs). Nevertheless, stakeholders remain uncertain about key issues which have resulted in heterogeneous reimbursement policies and varying levels of biosimilar uptake and differences in the approval processes for follow-on NBCDs between different markets.
With the imminent introduction of both follow-on NBCDs and biosimilars for multiple sclerosis (MS), researchers at MORSE compared biosimilars and NBCDs in Europe, the US and Canada with respect to MS [1].The commentary article defines biosimilars and follow-on NBCDs and provides an overview of how these products have been introduced in Europe, the US and Canada from a regulatory, health technology and reimbursement perspective. In addition, the article briefly explores the potential impact and outlook of biosimilar and follow-on NBCD products related to MS. Ultimately the article serves as a tool to inform clinicians within this disease space of this new class of products and how healthcare systems have been adapting to their use. Following this in-depth overview of the current landscape, MORSE provided recommendations to assist MS clinicians adapt to their evolving environment. These recommendations include: Biosimilars and follow-on NBCDs hold the potential to impact healthcare systems dramatically. As such, it is important for MS clinical specialists to possess a strong understanding of how these products are regulated, reviewed and reimbursed.
Conflict of interest Abstracted by Ms Sophia Gran-Ruaz, MORSE Consulting Inc, Toronto, Canada.
Related article
Reference Permission granted to reproduce for personal and non-commercial use only. All other reproduction, copy or reprinting of all or part of any ‘Content’ found on this website is strictly prohibited without the prior consent of the publisher. Contact the publisher to obtain permission before redistributing. Copyright – Unless otherwise stated all contents of this website are © 2018 Pro Pharma Communications International. All Rights Reserved.
The authors of the commentary [1] declared that there is no potential conflict of interest with respect to the research, authorship, and/or publication of this article.
Challenges in the regulation of NBCDs
1. Gran-Ruaz S, Mani A, O’Quinn S. An overview of biosimilars and non-biologic complex drugs in Europe, the United States, and Canada and their relevance to multiple sclerosis. Mult Scler. 2017;23(14):1824-9.
Comments (1)
Shop - Buy Medicine Online With Discount posted 10/01/2021 - by Get Flat 20% Discount on All Medicines.
BUY ADDERALL ONLINE buy soma online Buy Ambien Online Buy Codeine Online Buy Hydrocodone Online buy nowGenerics News Research General
- Perspectives of prescribing practices in public...Generics/Research | Posted 15/01/2021
- A European pharmaceutical strategy promoting ge...Generics/General | Posted 08/01/2021
- Familiarity with substitution of prescription g...Generics/Research | Posted 11/12/2020
- Cost savings after switching to generic tacrolimusGenerics/Research | Posted 04/12/2020
Biosimilars News Research General
- Biosimilars of trastuzumabBiosimilars/General | Posted 19/09/2014
- Biosimilars of pegfilgrastimBiosimilars/General | Posted 31/10/2014
- Biosimilars in Australia – a-flagging and susta...Biosimilars/General | Posted 08/01/2021
- Biosimilars of rituximabBiosimilars/General | Posted 27/02/2015