Amgen to buy out Japanese partner Astellas

Home/Pharma News | Posted 06/03/2020 post-comment0 Post your comment

US-based biotech giant Amgen has announced that it will dissolve its joint venture with the Japanese company Astellas in order to operate the unit independently. This means Astellas will become a wholly-owned Amgen affiliate.

Shaking hands V13D29

In 2013, Amgen formed a strategic alliance with Astellas Pharma (Astellas), a Japanese multinational pharmaceutical company. The joint venture has launched three drugs since this time, all of which are monoclonal antibodies:

• Repatha (evolocumab), a treatment for high cholesterol levels
• Evenity (romosozumab), a treatment for osteoporosis which reduces the risk of spinal fracture
• Blincyto (blinatumomab), a second-line treatment for a form of acute lymphoblastic leukaemia

At the JP Morgan healthcare conference in San Francisco, Amgen announced plans to dissolve the joint venture with Astellas in order to operate the unit independently.

The change will take place on 1 April 2020, at which point Amgen will purchase the 49% of shares in Amgen Astellas Biopharma that are currently held by Astellas. This will make Astellas a wholly-owned Amgen affiliate. The new company will be named Amgen KK and will have headquarters in midtown Tokyo.

The move reflects Amgen’s progression in the Asian market. The company expects a quarter of its growth in the next decade to come from the continent, according to Chief Executive Robert Bradway.

‘China and Japan are the second and third largest markets in our industry’, Bradway said. ‘In the case of China, it is a rapidly growing market ... Japan has an ageing population and we expect that will be a growth market for us’, he continued.

Amgen KK and Astellas will continue to co-promote the three drugs developed by the joint venture, and Astellas will remain responsible for their distribution and sales beyond 2020.

This is not the only venture Amgen has in Asia. In 2016, the company made a deal with Japan-based Daiichi Sankyo for biosimilars in Japan [1]. Then in 2017, the company made an agreement with China-based Simcere Pharmaceutical Group to co-develop and commercialize four copy biologicals in China [2].

Editor’s comment
It should be noted that copy biologicals approved in China might not have been authorized following as strict a regulatory process as is required for approval of biosimilars in the European Union. The EMA (European Medicines Agency) regulatory requirements ensure the same high standards of quality, safety and efficacy for biosimilars as for originator biologicals, and also include a rigorous comparability exercise with the reference product.

Related articles
Japanese opportunity for biosimilars

FDA approval for Amgen’s infliximab biosimilar Avsola

UnitedHealthcare to preferentially cover Amgen’s anticancer biosimilars

Biosimilars approved in Japan

1. GaBI Online - Generics and Biosimilars Initiative. Amgen and Daiichi Sankyo make deal for biosimilars in Japan []. Mol, Belgium: Pro Pharma Communications International; [cited 2020 Mar 6]. Available from:
2. GaBI Online - Generics and Biosimilars Initiative. Amgen and Simcere to collaborate on copy biologicals in China []. Mol, Belgium: Pro Pharma Communications International; [cited 2020 Mar 6]. Available from:

Permission granted to reproduce for personal and non-commercial use only. All other reproduction, copy or reprinting of all or part of any ‘Content’ found on this website is strictly prohibited without the prior consent of the publisher. Contact the publisher to obtain permission before redistributing. 

Copyright – Unless otherwise stated all contents of this website are © 2020 Pro Pharma Communications International. All Rights Reserved.

Source: Astellas

comment icon Comments (0)
Post your comment
Most viewed articles
About GaBI
Home/About GaBI Posted 06/08/2009
EU guidelines for biosimilars
EMA logo 1 V13C15
Home/Guidelines Posted 08/10/2010